Dr. Ana Maria Barral

College of Letters and Sciences
Mathematics and Natural Sciences

Ana Maria Barral is Assistant Professor at National University’s Costa Mesa campus. Originally a Biochemist, she has transitioned from cancer research to cell biology and microbiology. Her Ph.D. thesis focused on malignant melanoma, while her postdoctoral research explored a viral model of type 1 diabetes. After a few years working in the biotech industry she decided to return to academia as a full time educator. She is passionate about scientific teaching and is a participant in a number of research based course initiatives, such as the Genomics Education Partnership, the Small World Initiative, and the GCAT-SEEK consortium. Ana Barral is currently a Biology Scholar in the ASM Research Residency 2015 cohort.

Current Research Interests

Ana Barral is actively involved in incorporating authentic research experiences in science courses, often involving environmental samples and metagenomic analysis.
Her current research project focuses on the study of microbes attaching to plastic debris in the ocean.

Selected publications

Barral, AM, Makhluf, H, Soneral, P, Gasper B. 2014. Small World Initiative: crowdsourcing research of new antibiotics to enhance undergraduate biology teaching (618.41) FASEB J April 2014 28:618.41

Goodman, A., C. Arrigo, A. Barral, K. Jones, C. Peterson, J Roecklein-Canfield,W Leung, C. Shaffer, D. Lopatto, and S. Elgin. 2014. Genomics Education Partnership: a research-based approach to undergraduate teaching utilizing a centralized support system (618.39) FASEB J April 2014 28:618.39

Goodman, A.L., Barral, A.M., Riggs, W., Brown, M., Rule, G. 2012. The Open Learning Initiative: development and evaluation of free online content delivery system for introductory and advanced biology courses. Mol. Biol. Cell 23, 4663 (abstract #1001).

Yamazaki Y, Kohno K, Yasui H, Kiso Y, Neuteboom S, Barral AM, Potts B, Lloyd GK, Hayashi Y. 2009. Synthesis of biotin-tagged diketopiperazine-based anti-microtubule agents and tubulin photoaffinity labeling. Adv. Exp. Med. Biol. 611: 527.

Coppetiers, A., Barral A.M., Juedes, A., Wolfe, T., Rodrigo, E., Thery, C., Amigorena, S. and M. von Herrath. 2009. No significant CTL cross-priming by exosomes during murine lymphocytic choriomeningitis virus infection. Journal of Immunology, 182: 5.

Söderberg, A., Barral, A.M., Söderström, M., Sander, B. and A. Rosén. 2007. Redox-signaling transmitted in trans to neighboring cells by melanoma-derived TNF-containing exosomes. Free Radical Biology and Medicine, 43:90-99.

Barral, A.M., Thomas, H., Darwiche, R., Rodrigo, E., Christen, U., Ejrnaes, M. Wolfe, T., Kay, T. and M. von Herrath. 2006. Cytokine protection in diabetes through Suppressor of Cytokine Signaling (SOCS)-1. J. Autoimmunity, 27:166.

Rhode, A., Pauza, M.E., Barral, A.M., Rodrigo, E., Oldstone, M.B.A. and M. von Herrath. 2005. Islet-specific expression of CXCL10 causes spontaneous islet infiltration and accelerates diabetes development. Journal of Immunology, 175: 3516 - 3524.

Barral, A.M. and M. von Herrath, 2005. Exosomes: specific intercellular nano-shuttles? 2005. Current Immunology Reviews, 1: 1.

Barral, A.M., R. Källström, B. Sander, and A. Rosén. 2000. Thioredoxin, thioredoxin reductase and TNF-a _expressed in melanoma cells: correlation to resistance against cytotoxic attack.Melanoma Res 10:331.

Barral, A. M., A. Fernandez, M. E. Faxas, X. Perez, C. A. Garcia, and A. Rosen. 1997. Cell-cell adherence as a selection method for the generation of anti-melanoma monoclonal antibodies. J Immunol Methods 203:103.

Sahaf, B., A. Soderberg, G. Spyrou, A. M. Barral, K. Pekkari, A. Holmgren, and A. Rosen. 1997. Thioredoxin expression and localization in human cell lines: detection of full-length and truncated species. Exp Cell Res 236:181.

Amador, J. F., A. M. Vazquez, L. Cabrera, A. M. Barral, R. Gendelman, and M. Jondal. 1991. Toxic effects of interleukin-2-activated lymphocytes on vascular endothelial cells. Nat Immun Cell Growth Regul 10:207.

Contact Details

College of Letters and Sciences